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1

Innate Immune Mechanisms Dominate Elimination of Adenoviral Vectors Following In Vivo Administration

Worgall, Stefan, Wolff, Gerhard, Falck-Pedersen, Erik, Crystal, Ronald G.

Journal:

Human Gene Therapy

Year:

1997

Language:

english

File:

PDF, 4.53 MB

english, 1997

2

ChemInform Abstract: Synthesis of Heterocyclic Dipeptide Analogues.

Mette Lene Falck-Pedersen, Kjell Undheim

Journal:

Year:

1999

File:

PDF, 30 KB

1999

3

ChemInform Abstract: Palladium Mediated Substitutions and Rearrangements in Spiro[4,4]nonanes.

Doina Sirbu, Mette Lene Falck-Pedersen, Christian Roemming, Kjell Undheim

Journal:

Year:

1999

File:

PDF, 35 KB

1999

4

ChemInform Abstract: Palladium-Mediated Carbosubstitutions in Spiranes.

Mette Lene Falck-Pedersen, Christian Roemming, Kjell Undheim

Journal:

Year:

1999

File:

PDF, 33 KB

1999

5

ChemInform Abstract: Stereoselectivity in the Synthesis of Conformationally Constrained Vicinally Dihydroxylated Cyclic α-Amino Acids.

Kristin Hammer, Jing Wang, Mette Lene Falck-Pedersen, Christian Roemming, Kjell Undheim

Journal:

Year:

2000

File:

PDF, 33 KB

2000

6

ChemInform Abstract: Synthesis of Silacycloalkenes and Silaspirenes by Ru(II)-Catalyzed Ring-Closing Metathesis Reactions.

Iftikhar Ahmad, Mette Lene Falck-Pedersen, Kjell Undheim

Journal:

Year:

2001

File:

PDF, 35 KB

2001

7

ChemInform Abstract: The Pauson—Khand Reaction in Synthesis of Bicyclic Rigid α-Amino Acids.

Jing Wang, Mette Lene Falck-Pedersen, Christian Roemming, Kjell Undheim

Journal:

Year:

2001

File:

PDF, 31 KB

2001

8

Synthesis of spirane-bridged rigidified oxalkyl cyclopentadienyl ligands

Mette Lene Falck-Pedersen, Kjell Undheim

Journal:

Year:

2005

Language:

english

File:

PDF, 226 KB

english, 2005

9

Synthesis of silacycloalkenes and silaspirenes by Ru(II)-catalyzed ring-closing metathesis reactions

Iftikhar Ahmad, Mette Lene Falck-Pedersen, Kjell Undheim

Journal:

Journal of Organometallic Chemistry

Year:

2001

Language:

english

File:

PDF, 234 KB

english, 2001

10

Asymmetric synthesis of phenylbis(glycines)

Mette Lene Falck-Pedersen, Kjell Undheim

Journal:

Year:

1996

Language:

english

File:

PDF, 580 KB

english, 1996

11

Palladium mediated substitutions and rearrangements in spiro[4,4]nonanes

Doina Sirbu, Mette Lene Falck-Pedersen, Christian Rømming, Kjell Undheim

Journal:

Year:

1999

Language:

english

File:

PDF, 571 KB

english, 1999

12

Palladium-mediated carbosubstitutions in spiranes

Mette Lene Falck-Pedersen, Christian Rømming, Kjell Undheim

Journal:

Year:

1999

Language:

english

File:

PDF, 944 KB

english, 1999

13

Ectopic expression of thyrotropin releasing hormone (TRH) receptors in liver modulates organ function to regulate blood glucose by TRH

Wolff, Gerhard, Mastrangeli, Andrea, Heinflink, Marcos, Falck-Pedersen, Erik, Gershengorn, Marvin C., Crystal, Ronald G.

Journal:

Nature Genetics

Year:

1996

File:

PDF, 588 KB

1996

14

Sensitization of IFN-γ Jak-STAT signaling during macrophage activation

Hu, Xiaoyu, Herrero, Carmen, Li, Wai-Ping, Antoniv, Taras T., Falck-Pedersen, Erik, Koch, Alisa E., Woods, James M., Haines, G. Kenneth, Ivashkiv, Lionel B.

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 566 KB

english, 2002

15

Creation and Repair of Specific DNA Double-Strand Breaks in Vivo Following Infection with Adenovirus Vectors Expressing Saccharomyces cerevisiae HO Endonuclease

Andrea L. Nicolás, Patricia L. Munz, Erik Falck-Pedersen, C.S.H. Young

Journal:

Year:

2000

Language:

english

File:

PDF, 350 KB

english, 2000

16

Regulation of antibody secretion by hybridoma cells: II. mechanism of idiotype-induced suppression of antibody secretion by hybridoma cells

Poonam Gulati, Erik Falck-Pedersen, Gregory W. Siskind

Journal:

Cellular Immunology

Year:

1989

Language:

english

File:

PDF, 703 KB

english, 1989

17

Serotype 5 Adenovirus fiber (F7F41S) chimeric vectors incur packaging deficiencies when targeting peptides are inserted into Ad41 short fiber

John W. Schoggins, Erik Falck-Pedersen

Journal:

Year:

2009

Language:

english

File:

PDF, 1.44 MB

english, 2009

18

Regiospecific arylazo substitution into α-amanitin with retention of inhibitory properties against eukaryotic Class II RNA polymerase

ERIK FALCK-PEDERSEN, PAUL W. MORRIS, DUANE L. VENTON

Journal:

Chemical Biology & Drug Design

Year:

1983

Language:

english

File:

PDF, 605 KB

english, 1983

19

Cell-Specific Regulation of Nucleic Acid Sensor Cascades: a Controlling Interest in the Antiviral Response

Stein, S. C., Lam, E., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2012

Language:

english

File:

PDF, 980 KB

english, 2012

20

Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade

Lam, E., Stein, S., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

21

Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints

Janovitz, Tyler, Sadelain, Michel, Falck-Pedersen, Erik

Journal:

Virology Journal

Year:

2014

Language:

english

File:

PDF, 292 KB

english, 2014

22

Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse β-major globin terminator element

Falck-Pedersen, E., Logan, J., Shenk, T., Darnell, J.E.

Journal:

Year:

1985

Language:

english

File:

PDF, 2.00 MB

english, 1985

23

A poly(A) Addition Site and a Downstream Termination Region are Required for Efficient Cessation of Transcription by RNA Polymerase II in the Mouse βmaj-globin Gene

John Logan, Erik Falck-Pedersen, James E. Darnell and Thomas Shenk

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.17 MB

english, 1987

24

Adenovirus-Mediated Gene Delivery into Neuronal Precursors of the Adult Mouse Brain

Sung Ok Yoon, Carlos Lois, Mauricio Alvirez, Arturo Alvarez-Buylla, Erik Falck-Pedersen and Moses V. Chao

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.62 MB

english, 1996

25

Tumor Necrosis Factor α Plays a Central Role in Immune-Mediated Clearance of Adenoviral Vectors

Keith B. Elkon, Chau-Ching Liu, Jason G. Gall, Jose Trevejo, Michael W. Marino, Karil A. Abrahamsen, Xin Song, Jun-Liang Zhou, Lloyd J. Old, Ronald G. Crystal and Erik Falck-Pedersen

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.57 MB

english, 1997

26

Sensing Adenovirus Infection: Activation of Interferon Regulatory Factor 3 in RAW 264.7 Cells

Stein, Saskia C., Falck-Pedersen, Erik

Journal:

Journal of Virology

Year:

2012

Language:

english

File:

PDF, 2.06 MB

english, 2012

27

Interaction of several class II and III RNA polymerases with two families of 7'-substituted .alpha.-amanitin

Falck-Pedersen, Erik, Neuman, Wilma, Morris, Paul W.

Journal:

Year:

1982

Language:

english

File:

PDF, 864 KB

english, 1982

28

Unabated Adenovirus Replication following Activation of the cGAS/STING-Dependent Antiviral Response in Human Cells

Lam, E., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2014

Language:

english

File:

PDF, 10.51 MB

english, 2014

29

Stereoselectivity in the synthesis of conformationally constrained vicinally dihydroxylated cyclic α-amino acids

Hammer, Kristin, Wang, Jing, Falck-Pedersen, Mette Lene, Rømming, Christian, Undheim, Kjell

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

30

Transgene Expression After Rep-Mediated Site-Specific Integration into Chromosome 19

Philpott, Nicola J., Gomos, Janette, Falck-Pedersen, Erik

Journal:

Human Gene Therapy

Year:

2004

Language:

english

File:

PDF, 728 KB

english, 2004

31

THE PAUSON-KHAND REACTION IN SYNTHESIS OF BICYCLIC RIGID α-AMINO ACIDS

Wang, Jing, Falck-Pedersen, Mette Lene, Rømming, Christian, Undheim, Kjell

Journal:

Synthetic Communications

Year:

2001

Language:

english

File:

PDF, 157 KB

english, 2001

32

“Sero-Switch” Adenovirus-Mediated In Vivo Gene Transfer: Circumvention of Anti-Adenovirus Humoral Immune Defenses Against Repeat Adenovirus Vector Administration by Changing the Adenovirus Serotype

Mastrangeli, Andrea, Harvey, Ben-Gary, Yao, Jeffrey, Wolff, Gerhard, Kovesdi, Imre, Crystal, Ronald G., Falck-Pedersen, Erik

Journal:

Human Gene Therapy

Year:

1996

Language:

english

File:

PDF, 7.53 MB

english, 1996

33

Circumvention of Anti-Adenovirus Neutralizing Immunity by Administration of an Adenoviral Vector of an Alternate Serotype

Mack, Charles A., Song, Wen-Ru, Carpenter, Heather, Wickham, Tom J., Kovesdi, Imre, Harvey, Ben-Gary, Magovern, Christopher J., Isom, O. Wayne, Rosengart, Todd, Falck-Pedersen, Eric, Hackett, Neil R.,

Journal:

Human Gene Therapy

Year:

1997

Language:

english

File:

PDF, 1.02 MB

english, 1997

34

Soluble CD8 Attenuates Cytotoxic T Cell Responses Against Replication-Defective Adenovirus Affording Transprotection of Transgenes In Vivo

Peng, Y., Falck-Pedersen, E., Elkon, K. B.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 1.20 MB

english, 2000

35

TNF- -dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection

Trevejo, J. M., Marino, M. W., Philpott, N., Josien, R., Richards, E. C., Elkon, K. B., Falck-Pedersen, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 266 KB

english, 2001

36

Adenovirus Induction of IRF3 Occurs through a Binary Trigger Targeting Jun N-Terminal Kinase and TBK1 Kinase Cascades and Type I Interferon Autocrine Signaling

Nociari, M., Ocheretina, O., Murphy, M., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2009

Language:

english

File:

PDF, 880 KB

english, 2009

37

Influence of Fiber Detargeting on Adenovirus-Mediated Innate and Adaptive Immune Activation

Schoggins, J. W., Nociari, M., Philpott, N., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

38

A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19

Philpott, N. J., Gomos, J., Berns, K. I., Falck-Pedersen, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 202 KB

english, 2002

39

Subgroup B and F Fiber Chimeras Eliminate Normal Adenovirus Type 5 Vector Transduction In Vitro and In Vivo

Schoggins, J. W., Gall, J. G. D., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2003

Language:

english

File:

PDF, 618 KB

english, 2003

40

Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF- induction pathway

Philpott, N. J., Nociari, M., Elkon, K. B., Falck-Pedersen, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 503 KB

english, 2004

41

Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells

Diaz, F., Gravotta, D., Deora, A., Schreiner, R., Schoggins, J., Falck-Pedersen, E., Rodriguez-Boulan, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 1.93 MB

english, 2009

42

Fiber and Penton Base Capsid Modifications Yield Diminished Adenovirus Type 5 Transduction and Proinflammatory Gene Expression with Retention of Antigen-Specific Humoral Immunity

Schoggins, J. W., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2006

Language:

english

File:

PDF, 466 KB

english, 2006

43

High-Throughput Sequencing Reveals Principles of Adeno-Associated Virus Serotype 2 Integration

Janovitz, T., Klein, I. A., Oliveira, T., Mukherjee, P., Nussenzweig, M. C., Sadelain, M., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

44

Sensing Infection by Adenovirus: Toll-Like Receptor-Independent Viral DNA Recognition Signals Activation of the Interferon Regulatory Factor 3 Master Regulator

Nociari, M., Ocheretina, O., Schoggins, J. W., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2007

Language:

english

File:

PDF, 656 KB

english, 2007

45

Adeno-Associated Virus Type 2 p5 Promoter: a Rep-Regulated DNA Switch Element Functioning in Transcription, Replication, and Site-Specific Integration

Murphy, M., Gomos-Klein, J., Stankic, M., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2007

Language:

english

File:

PDF, 507 KB

english, 2007

46

Highly Divergent Integration Profile of Adeno-Associated Virus Serotype 5 Revealed by High-Throughput Sequencing

Janovitz, T., Oliveira, T., Sadelain, M., Falck-Pedersen, E., Imperiale, M. J.

Journal:

Journal of Virology

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

47

Adeno-Associated Virus Site-Specific Integration and AAVS1 Disruption

Hamilton, H., Gomos, J., Berns, K. I., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2004

Language:

english

File:

PDF, 1.03 MB

english, 2004

48

Manipulating Adenovirus Hexon Hypervariable Loops Dictates Immune Neutralisation and Coagulation Factor X-dependent Cell Interaction In Vitro and In Vivo

Ma, Jiangtao, Duffy, Margaret R., Deng, Lin, Dakin, Rachel S., Uil, Taco, Custers, Jerome, Kelly, Sharon M., McVey, John H., Nicklin, Stuart A., Baker, Andrew H., Falck-Pedersen, Erik

Journal:

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

49

Efficient Integration of Recombinant Adeno-Associated Virus DNA Vectors Requires a p5-rep Sequence in cis

Philpott, N. J., Giraud-Wali, C., Dupuis, C., Gomos, J., Hamilton, H., Berns, K. I., Falck-Pedersen, E.

Journal:

Journal of Virology

Year:

2002

Language:

english

File:

PDF, 803 KB

english, 2002

50

Variation in Adenovirus Transgene Expression between BALB/c and C57BL/6 Mice Is Associated with Differences in Interleukin-12 and Gamma Interferon Production and NK Cell Activation

Peng, Y., Falck-Pedersen, E., Elkon, K. B.

Journal:

Journal of Virology

Year:

2001

Language:

english

File:

PDF, 2.18 MB

english, 2001

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